149204-50-2
149204-50-2
Chemical Structure
MG-H1
- CAS No.: 149204-50-2
- Formula:C9H16N4O3
- Molecular Weight:228.25
InChIKey: KGQMQNPFMOBJCY-GDVGLLTNSA-N
SMILES: OC([C@@H](N)CCCNC(NC1C)=NC1=O)=O
Biological Activity: MG-H1 is a RAGE ligand, advanced glycation end product cross-link, and pathogenic mediator with relevance to diabetic vasculopathy. MG-H1 binds to RAGE and competes with CM1 for RAGE binding on endothelial cells. MG-H1 is implicated in diabetic vasculopathy pathogenesis. MG-H1 can be used for the research of diabetic vasculopathy[1].
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MG-H1 | MG-H1 is a RAGE ligand, advanced glycation end product cross-link, and pathogenic mediator with relevance to diabetic vasculopathy. MG-H1 binds to RAGE and competes with CM1 for RAGE binding on endothelial cells. MG-H1 is implicated in diabetic vasculopathy pathogenesis. MG-H1 can be used for the research of diabetic vasculopathy. | |||||||||||||||||||||
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References
- [1]. Feng L, et al. Competitive binding between 4,4'-diphenylmethane-bis(methyl) carbamate and RAGE ligand MG-H1 on human umbilical vein endothelial cell by cell membrane chromatography. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2012 Jan 15;881-882:55-62. [Content Brief]
