1527473-30-8
1527473-30-8
Chemical Structure
PF-06454589
- CAS No.: 1527473-30-8
- Formula:C14H16N6O
- Molecular Weight:284.32
IUPAC Name: 4-(5-(1-methyl-1H-pyrazol-4-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl)morpholine
InChIKey: VNWKCLDQBNSJJO-UHFFFAOYSA-N
SMILES: CN1N=CC(C2=CNC3=NC=NC(N4CCOCC4)=C32)=C1
Biological Activity: PF-06447475 is a highly potent, selective, brain penetrant LRRK2 kinase inhibitor with IC50 values of 3 nM and 11 nM for WT LRRK and G2019S LRRK2, respectively. PF-06447475 can be used for parkinson's disease (PD) research[1].
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PF-06454589 | 99.91% | PF-06447475 is a highly potent, selective, brain penetrant LRRK2 kinase inhibitor with IC50 values of 3 nM and 11 nM for WT LRRK and G2019S LRRK2, respectively. PF-06447475 can be used for parkinson's disease (PD) research. | ||||||||||||||||||||
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References
Keywords
