1532515-60-8
1532515-60-8
Chemical Structure
TRPV4/TRPA1-IN-1
- CAS No.: 1532515-60-8
- Formula:C25H25N3S
- Molecular Weight:399.56
IUPAC Name: N-(4-(2-(benzyl(methyl)amino)ethyl)phenyl)-4-phenylthiazol-2-amine
InChIKey: JIVNFHNFDYSFCB-UHFFFAOYSA-N
SMILES: N1=C(SC=C1C=2C=CC=CC2)NC3=CC=C(C=C3)CCN(C)CC=4C=CC=CC4
Biological Activity: TRPV4/TRPA1-IN-1 is a TRPV4/TRPA1 inhibitor that suppresses TRPV4/TRPA1-mediated calcium influx. TRPV4/TRPA1-IN-1 alleviates pain behaviors in a mouse trigeminal stimulation pain model and inhibits inflammation and pain-related behaviors in a mouse acute pancreatitis model. TRPV4/TRPA1-IN-1 can be used in research on acute pancreatitis[1].
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TRPV4/TRPA1-IN-1 | TRPV4/TRPA1-IN-1 is a TRPV4/TRPA1 inhibitor that suppresses TRPV4/TRPA1-mediated calcium influx. TRPV4/TRPA1-IN-1 alleviates pain behaviors in a mouse trigeminal stimulation pain model and inhibits inflammation and pain-related behaviors in a mouse acute pancreatitis model. TRPV4/TRPA1-IN-1 can be used in research on acute pancreatitis. | |||||||||||||||||||||
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