154447-41-3
Chemical Structure
L 366763
- CAS No.: 154447-41-3
- Formula:C29H48N12O11S2
- Molecular Weight:804.90
IUPAC Name: (S)-3-(2-((S)-2-((S)-1-(acetyl-L-cysteinyl-L-asparaginyl)pyrrolidine-2-carboxamido)-5-guanidinopentanamido)acetamido)-4-(((R)-1-amino-3-mercapto-1-oxopropan-2-yl)amino)-4-oxobutanoic acid
InChIKey: PXQMYFXMGZFGFB-DYKIIFRCSA-N
SMILES: CC(N[C@@H](CS)C(N[C@@H](CC(N)=O)C(N1[C@@H](CCC1)C(N[C@@H](CCCNC(N)=N)C(NCC(N[C@@H](CC(O)=O)C(N[C@@H](CS)C(N)=O)=O)=O)=O)=O)=O)=O)=O
Biological Activity: L 366763 is a potent peptide that acts as a fibrinogen receptor antagonist, preventing collagen-induced platelet aggregation and adhesion. L 366763 inhibits platelet deposition and maintains blood flow in a baboon thrombosis model, significantly prolonging bleeding time. L 366763 has antithrombotic efficacy, whereas recombinant LAPP does not have the same effect[1].
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L 366763 | L 366763 is a potent peptide that acts as a fibrinogen receptor antagonist, preventing collagen-induced platelet aggregation and adhesion. L 366763 inhibits platelet deposition and maintains blood flow in a baboon thrombosis model, significantly prolonging bleeding time. L 366763 has antithrombotic efficacy, whereas recombinant LAPP does not have the same effect. | |||||||||||||||||||||
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