156604-79-4
Chemical Structure
Dexketoprofen (trometamol)
Synonym(s): Dexketoprofen tromethamine salt
- CAS No.: 156604-79-4
- Formula:C20H25NO6
- Molecular Weight:375.42
IUPAC Name: 2-amino-2-(hydroxymethyl)propane-1,3-diol (S)-2-(3-benzoylphenyl)propanoate
InChIKey: QUZMDHVOUNDEKW-MERQFXBCSA-N
SMILES: O=C(C1=CC=CC=C1)C2=CC([C@H](C)C(O)=O)=CC=C2.NC(CO)(CO)CO
Biological Activity: Dexketoprofen trometamol (Dexketoprofen tromethamine salt) is an orally active non-selective COX inhibitor. Dexketoprofen trometamol has a pain-relieving effect, anti-inflammatory effect and anti-cancer effect[1][2][3][4][5].
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Dexketoprofen (trometamol) | 99.73% | Dexketoprofen trometamol (Dexketoprofen tromethamine salt) is an orally active non-selective COX inhibitor. Dexketoprofen trometamol has a pain-relieving effect, anti-inflammatory effect and anti-cancer effect. | ||||||||||||||||||||
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Dexketoprofen (trometamol) (Standard) | ≥98% | Dexketoprofen (trometamol) (Standard) is the analytical standard of Dexketoprofen (trometamol). This product is intended for research and analytical applications. Dexketoprofen trometamol (Dexketoprofen tromethamine salt) is an orally active non-selective COX inhibitor. Dexketoprofen trometamol has a pain-relieving effect. | ||||||||||||||||||||
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Dexketoprofen-d3 (trometamol) | Dexketoprofen-d3 (trometamol) is deuterium labeled Dexketoprofen trometamol. | |||||||||||||||||||||
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- [1]. Magdi Hanna, et al. A review of dexketoprofen trometamol in acute pain. Curr Med Res Opin. 2019 Feb;35(2):189-202. [Content Brief]
- [2]. Romero-Alejo E, et al. Antihyperalgesic effects of dexketoprofen and tramadol in a model of postoperative pain in mice - effects on glial cell activation. J Pharm Pharmacol. 2016 Aug;68(8):1041-50. [Content Brief]
- [3]. Büyükfidan D, et al. The effects of dexketoprofen trometamol on incisional wound healing in a rat model: 9AP7-7[J]. European Journal of Anaesthesiology| EJA, 2011, 28: 144-145.
- [4]. Marinov L, et al. The effects of meloxicam, lornoxicam, ketoprofen, and dexketoprofen on human cervical, colorectal, and mammary carcinoma cell lines[J]. Pharmacia, 2024, 71: 1-12.
- [5]. Soliman S M, et al. The deleterious effect of xylene-induced ear edema in rats: protective role of dexketoprofen trometamol transdermal invasomes via inhibiting the oxidative stress/NF-κB/COX-2 pathway[J]. International Journal of Pharmaceutics, 2023, 631: 122525. [Content Brief]