1580-42-3
1580-42-3
Chemical Structure
SARS-CoV-2-IN-15
- CAS No.: 1580-42-3
- Formula:C14H9ClF3NO2
- Molecular Weight:315.67
IUPAC Name: 5-chloro-2-hydroxy-N-(3-(trifluoromethyl)phenyl)benzamide
InChIKey: OAMVIBKEICGPKK-UHFFFAOYSA-N
SMILES: O=C(NC1=CC=CC(C(F)(F)F)=C1)C2=CC(Cl)=CC=C2O
Biological Activity: SARS-CoV-2-IN-15 (compound 11) is a potent inhibitor of SARS-CoV-2 with an IC50 of 0.49 μM. SARS-CoV-2-IN-15 is a niclosamide analogue. SARS-CoV-2-IN-15 contains higher stability in human plasma and liver S9 enzymes assay than niclosamide, which can improve bioavailability and half-life when administered orally[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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SARS-CoV-2-IN-15 | 99.65% | SARS-CoV-2-IN-15 (compound 11) is a potent inhibitor of SARS-CoV-2 with an IC50 of 0.49 μM. SARS-CoV-2-IN-15 is a niclosamide analogue. SARS-CoV-2-IN-15 contains higher stability in human plasma and liver S9 enzymes assay than niclosamide, which can improve bioavailability and half-life when administered orally. | ||||||||||||||||||||
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References
Keywords
