158446-29-8
Chemical Structure
Dorrigocin A
- CAS No.: 158446-29-8
- Formula:C27H41NO8
- Molecular Weight:507.62
IUPAC Name: (2E,6E,8S,9S,10R,11E,13R,14S)-18-(2,6-dioxopiperidin-4-yl)-9,13-dihydroxy-8-methoxy-10,12,14-trimethyl-15-oxooctadeca-2,6,11-trienoic acid
InChIKey: HJCZOTBHYAPUHT-LPYGBFRZSA-N
SMILES: O=C(O)/C=C/CC/C=C/[C@H](OC)[C@@H](O)[C@H](C)/C=C(C)/[C@H](O)[C@H](C)C(CCCC(C1)CC(NC1=O)=O)=O
Biological Activity: Dorrigocin A is an analog of Migrastatin (HY-121452). Dorrigocin A can inhibit the carboxymethyltransferase involved in Ras processing and reverse the morphology of ras-transformed NIH/3T3 cells. Dorrigocin A is promising for research of anti-cancer and anti-arthritis agents[1].
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Dorrigocin A | Dorrigocin A is an analog of Migrastatin (HY-121452). Dorrigocin A can inhibit the carboxymethyltransferase involved in Ras processing and reverse the morphology of ras-transformed NIH/3T3 cells. Dorrigocin A is promising for research of anti-cancer and anti-arthritis agents. | |||||||||||||||||||||
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Keywords
