159013-54-4
Chemical Structure
BIBP3226
- CAS No.: 159013-54-4
- Formula:C27H31N5O3
- Molecular Weight:473.57
IUPAC Name: (R)-5-((diaminomethylene)amino)-2-(2,2-diphenylacetamido)-N-(4-hydroxybenzyl)pentanamide
InChIKey: KUWBXRGRMQZCSS-HSZRJFAPSA-N
SMILES: O=C([C@@H](CCC/N=C(N)\N)NC(C(C1=CC=CC=C1)C2=CC=CC=C2)=O)NCC3=CC=C(C=C3)O
Biological Activity: BIBP3226 is a potent and selective neuropeptide Y Y1 (NPY Y1) and neuropeptide FF (NPFF) receptor antagonist, with Kis of 1.1, 79, and 108 nM for rNPY Y1, hNPFF2, and rNPFF, respectively. BIBP3226 displays anxiogenic-like effect[1][2].
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BIBP3226 | 98.78% | BIBP3226 is a potent and selective neuropeptide Y Y1 (NPY Y1) and neuropeptide FF (NPFF) receptor antagonist, with Kis of 1.1, 79, and 108 nM for rNPY Y1, hNPFF2, and rNPFF, respectively. BIBP3226 displays anxiogenic-like effect. | ||||||||||||||||||||
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Keywords