159094-94-7
159094-94-7
Chemical Structure
NO-711
Synonym(s): NNC-711 free acid
- CAS No.: 159094-94-7
- Formula:C21H22N2O3
- Molecular Weight:350.41
IUPAC Name: 1-(2-(((diphenylmethylene)amino)oxy)ethyl)-1,2,5,6-tetrahydropyridine-3-carboxylic acid
InChIKey: NGNALWDRPKNJGR-UHFFFAOYSA-N
SMILES: O=C(C1=CCCN(CCO/N=C(C2=CC=CC=C2)\C3=CC=CC=C3)C1)O
Biological Activity: NO-711 (NNC-711) free acid is a novel potent and selective inhibitor of γ-aminobutyric acid uptake. NO-711 inhibits synaptosomal (IC50 = 47 nM), neuronal (IC50 = 1238 nM) and glial (IC50 = 636 nM) GABA uptake in vitro[1].
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NO-711 | NO-711 (NNC-711) free acid is a novel potent and selective inhibitor of γ-aminobutyric acid uptake. NO-711 inhibits synaptosomal (IC50 = 47 nM), neuronal (IC50 = 1238 nM) and glial (IC50 = 636 nM) GABA uptake in vitro. | |||||||||||||||||||||
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References
Keywords
