1592640-75-9
Chemical Structure
TG2-IN-3h
- CAS No.: 1592640-75-9
- Formula:C21H26N4O4S
- Molecular Weight:430.52
IUPAC Name: N-(2-(4-((5-(dimethylamino)naphthalen-1-yl)sulfonyl)piperazin-1-yl)-2-oxoethyl)acrylamide
InChIKey: PBRTXVPCMZIRCX-UHFFFAOYSA-N
SMILES: O=C(C=C)NCC(=O)N1CCN(CC1)S(=O)(=O)C2=CC=CC=3C2=CC=CC3N(C)C
Biological Activity: TG2-IN-3h (Compound 3h) is a transglutaminase (TG2) inhibitor (hTG2: IC50 = 6nM). TG2-IN-3h inhibits endothelial cell migration and angiogenesis. TG2-IN-3h alleviates renal fibrosis in a mouse model of hypertensive nephropathy. TG2-IN-3h can be used in research on metabolic diseases such as hypertensive nephropathy and cardiovascular and cerebrovascular diseases such as pathological angiogenesis[1].
| Cat. No. | Nom du produit | Pureté | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
TG2-IN-3h | TG2-IN-3h (Compound 3h) is a transglutaminase (TG2) inhibitor (hTG2: IC50 = 6nM). TG2-IN-3h inhibits endothelial cell migration and angiogenesis. TG2-IN-3h alleviates renal fibrosis in a mouse model of hypertensive nephropathy. TG2-IN-3h can be used in research on metabolic diseases such as hypertensive nephropathy and cardiovascular and cerebrovascular diseases such as pathological angiogenesis. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
Keywords
