159776-68-8
Chemical Structure
Linetastine
- CAS No.: 159776-68-8
- Formula:C35H40N2O6
- Molecular Weight:584.70
IUPAC Name: 4-((1E,3E)-5-((2-(4-(benzhydryloxy)piperidin-1-yl)ethyl)amino)-5-oxopenta-1,3-dien-1-yl)-2-methoxyphenyl ethyl carbonate
InChIKey: LUOUCHOLMUUZBO-SVSXJNCISA-N
SMILES: O=C(/C=C/C=C/C1=CC=C(C(OC)=C1)OC(OCC)=O)NCCN2CCC(CC2)OC(C3=CC=CC=C3)C4=CC=CC=C4
Biological Activity: Linetastine is an orally active and potent 5-Lipoxygenase inhibitor. Linetastine shows antihistamine activity. Linetastine inhibits leukotriene production and antagonizes the effect of histamine. Linetastine inhibits the release of leukotrienes B4 and C4 from calcium ionophore-stimulated human leukocytes[1].
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Linetastine | Linetastine is an orally active and potent 5-Lipoxygenase inhibitor. Linetastine shows antihistamine activity. Linetastine inhibits leukotriene production and antagonizes the effect of histamine. Linetastine inhibits the release of leukotrienes B4 and C4 from calcium ionophore-stimulated human leukocytes. | |||||||||||||||||||||
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