1607831-82-2
Chemical Structure
BKN-1
- CAS No.: 1607831-82-2
- Formula:C31H29IN2
- Molecular Weight:556.48
InChIKey: MSKGZANNCMICAY-UHFFFAOYSA-M
SMILES: CCN1C2=C(C=C(/C=C/C3=[N+](C)C(C=CC4=C5C=CC=C4)=C5C3(C)C)C=C2)C6=C1C=CC=C6.[I-]
Biological Activity: BKN-1 is a bifunctional ligand that can not only track the formation of mtG4s (G-quadruplexes, four-stranded DNA structures containing Hoogsteen bonds) through far-red emission, but can also induce mitochondrial dysfunction. BKN-1 has anti-tumor activity and may cause mtDNA loss, damage mitochondrial integrity, reduce ATP levels, and trigger ROS imbalance, leading to apoptosis and autophagy[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
BKN-1 | BKN-1 is a bifunctional ligand that can not only track the formation of mtG4s (G-quadruplexes, four-stranded DNA structures containing Hoogsteen bonds) through far-red emission, but can also induce mitochondrial dysfunction. BKN-1 has anti-tumor activity and may cause mtDNA loss, damage mitochondrial integrity, reduce ATP levels, and trigger ROS imbalance, leading to apoptosis and autophagy. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
Keywords
