161748-40-9
161748-40-9
Chemical Structure
BTS-67582
- CAS No.: 161748-40-9
- Formula:C17H24N4O5
- Molecular Weight:364.40
IUPAC Name: 1,1-dimethyl-3-(2-morpholinophenyl)guanidine fumarate
InChIKey: FFEKJBVVAJTQST-WLHGVMLRSA-N
SMILES: N=C(NC1=CC=CC=C1N2CCOCC2)N(C)C.O=C(O)/C=C/C(O)=O
Biological Activity: BTS-67582 is an orally active nonsulfonylurea insulinotropic agent and potassium channel blocker. BTS-67582 affects the K+ ATP channel in the islet cell but at a different binding site than the sulfonylureas. BTS-67582 is an antidiabetic agent[1][2].
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BTS-67582 | BTS-67582 is an orally active nonsulfonylurea insulinotropic agent and potassium channel blocker. BTS-67582 affects the K+ ATP channel in the islet cell but at a different binding site than the sulfonylureas. BTS-67582 is an antidiabetic agent. | |||||||||||||||||||||
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References
- [1]. Skillman CA, Raskin P. A double-masked placebo-controlled trial assessing effects of various doses of BTS 67,582, a novel insulinotropic agent, on fasting hyperglycemia in NIDDM patients. Diabetes Care. 1997 Apr;20(4):591-6. 7,582, a Novel Insulinotropic Agent, on Fasting Hyperglycemia in NIDDM Patients [Content Brief]
- [2]. Louchami K, et al. Effect of 1,1-dimethyl-2-[2-morpholinophenyl]guanidine fumarate on pancreatic islet function. Eur J Pharmacol. 1998 Jul 10;352(2-3):289-97. [Content Brief]
