1619269-19-0
1619269-19-0
Chemical Structure
Tau-aggregation-IN-1
- CAS No.: 1619269-19-0
- Formula:C28H37N5O2S
- Molecular Weight:507.69
IUPAC Name: (R)-4'-(4-(2-((2-amino-4,5,6,7-tetrahydrobenzo[d]thiazol-6-yl)(propyl)amino)ethyl)piperazin-1-yl)-[1,1'-biphenyl]-3,4-diol
InChIKey: IGXNQKRXZZPFHF-HSZRJFAPSA-N
SMILES: OC(C=C1C(C=C2)=CC=C2N(CC3)CCN3CCN([C@H]4CC5=C(N=C(S5)N)CC4)CCC)=C(C=C1)O
Biological Activity: Tau-aggregation-IN-1 (Compound D-519) is a tau441 protein aggregation inhibitor with an IC50 of 21 µM. Tau-aggregation-IN-1 is also a dopamine D2 and D3 receptor agonist[1].
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Tau-aggregation-IN-1 | Tau-aggregation-IN-1 (Compound D-519) is a tau441 protein aggregation inhibitor with an IC50 of 21 µM. Tau-aggregation-IN-1 is also a dopamine D2 and D3 receptor agonist. | |||||||||||||||||||||
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