163217-70-7
163217-70-7
Chemical Structure
4-Hydroxy Atorvastatin lactone
Synonym(s): P-Hydroxyatorvastatin lactone; 4-ATL
- CAS No.: 163217-70-7
- Formula:C33H33FN2O5
- Molecular Weight:556.62
IUPAC Name: 5-(4-fluorophenyl)-1-(2-((2R,4R)-4-hydroxy-6-oxotetrahydro-2H-pyran-2-yl)ethyl)-N-(4-hydroxyphenyl)-2-isopropyl-4-phenyl-1H-pyrrole-3-carboxamide
InChIKey: KDJMDZSAAFACAM-KAYWLYCHSA-N
SMILES: O=C(C1=C(C(C)C)N(CC[C@@H]2C[C@@H](O)CC(O2)=O)C(C3=CC=C(F)C=C3)=C1C4=CC=CC=C4)NC5=CC=C(O)C=C5
Biological Activity: 4-Hydroxy Atorvastatin lactone is a metabolite of Atorvastatin (HY-B0589). Atorvastatin is an orally active HMG-CoA reductase inhibitor, has the ability to effectively decrease blood lipids[1].
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4-Hydroxy Atorvastatin lactone | 4-Hydroxy Atorvastatin lactone is a metabolite of Atorvastatin (HY-B0589). Atorvastatin is an orally active HMG-CoA reductase inhibitor, has the ability to effectively decrease blood lipids. | |||||||||||||||||||||
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4-Hydroxy Atorvastatin lactone-d5 | 4-Hydroxy Atorvastatin lactone-d5 is deuterium labeled 4-hydroxy Atorvastatin lactone. | |||||||||||||||||||||
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References
