16346-97-7
Chemical Structure
Topoisomerase IIα-IN-9
Synonym(s): 4,4'-Sulfonylbis(2-methylphenol)
- CAS No.: 16346-97-7
- Formula:C14H14O4S
- Molecular Weight:278.32
IUPAC Name: 4,4'-sulfonylbis(2-methylphenol)
InChIKey: XTEGBRKTHOUETR-UHFFFAOYSA-N
SMILES: OC1=CC=C(S(=O)(C2=CC=C(O)C(C)=C2)=O)C=C1C
Biological Activity: Topoisomerase IIα-IN-9 (NSC85582) is a bisphenol compound that has a moderate inhibitory effect on DNA topoisomerase Topoisomerase II (IC50: 571 μM). Topoisomerase IIα-IN-9 also exhibits a certain cell growth inhibitory effect, with IC50s of 117 μM and 218 μM for K562 and CHO, respectively[1].
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Topoisomerase IIα-IN-9 | Topoisomerase IIα-IN-9 (NSC85582) is a bisphenol compound that has a moderate inhibitory effect on DNA topoisomerase Topoisomerase II (IC50: 571 μM). Topoisomerase IIα-IN-9 also exhibits a certain cell growth inhibitory effect, with IC50s of 117 μM and 218 μM for K562 and CHO, respectively. | |||||||||||||||||||||
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Keywords