163490-78-6
163490-78-6
Chemical Structure
hnNOS-IN-3
- CAS No.: 163490-78-6
- Formula:C10H12ClF3N2S
- Molecular Weight:284.73
IUPAC Name: ethyl (4-(trifluoromethyl)phenyl)carbamimidothioate hydrochloride
InChIKey: UVJQIYZYQQKIAC-UHFFFAOYSA-N
SMILES: N=C(SCC)NC1=CC=C(C(F)(F)F)C=C1.[H]Cl
Biological Activity: hnNOS-IN-3 (compound 39) is a selective nNOS inhibitor, with a Ki of 0.32 μM. The nNOS binding of hnNOS-IN-3 is competitive with L-arginine. The selectivity of hnNOS-IN-3 for nNOS versus iNOS (Ki=37 μM) and eNOS (Ki=9.4 μM) is 115-fold and 29-fold, respectively[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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hnNOS-IN-3 | 98.60% | hnNOS-IN-3 (compound 39) is a selective nNOS inhibitor, with a Ki of 0.32 μM. The nNOS binding of hnNOS-IN-3 is competitive with L-arginine. The selectivity of hnNOS-IN-3 for nNOS versus iNOS (Ki=37 μM) and eNOS (Ki=9.4 μM) is 115-fold and 29-fold, respectively. | ||||||||||||||||||||
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References
Keywords
