hnNOS-IN-3
Based on 1 Customer Validation
hnNOS-IN-3 (compound 39) is a selective nNOS inhibitor, with a Ki of 0.32 μM. The nNOS binding of hnNOS-IN-3 is competitive with L-arginine. The selectivity of hnNOS-IN-3 for nNOS versus iNOS (Ki=37 μM) and eNOS (Ki=9.4 μM) is 115-fold and 29-fold, respectively.
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- Pureté : 98.60%
- CAS No.: 163490-78-6
- Formule: C10H12ClF3N2S
- Masse moléculaire:284.73
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Stockage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Chemical Information
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Solvant et solubilité
- Pureté et documentation
- Références
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Help & FAQs
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α-Guanidinoglutaric acidGuanidino Compound
Activité biologique
Description
IC50 & Target
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nNOS 0.32 μM (Ki) |
eNOS 9.4 μM (Ki) |
iNOS 37 μM (Ki) |
Chemical Information
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CAS No. 163490-78-6
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Appearance Solid
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Masse moléculaire 284.73
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Formule C10H12ClF3N2S
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Color White to off-white
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SMILES
N=C(SCC)NC1=CC=C(C(F)(F)F)C=C1.[H]Cl
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvant et solubilité
In Vitro:
H2O : 12.5 mg/mL (43.90 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureté et documentation
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Fiche technique (269 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Instruction de manipulation (2659 KB)
Références
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 3.5121 mL | 17.5605 mL | 35.1210 mL | 87.8025 mL |
| 5 mM | 0.7024 mL | 3.5121 mL | 7.0242 mL | 17.5605 mL | |
| 10 mM | 0.3512 mL | 1.7560 mL | 3.5121 mL | 8.7802 mL | |
| 15 mM | 0.2341 mL | 1.1707 mL | 2.3414 mL | 5.8535 mL | |
| 20 mM | 0.1756 mL | 0.8780 mL | 1.7560 mL | 4.3901 mL | |
| 25 mM | 0.1405 mL | 0.7024 mL | 1.4048 mL | 3.5121 mL | |
| 30 mM | 0.1171 mL | 0.5853 mL | 1.1707 mL | 2.9267 mL | |
| 40 mM | 0.0878 mL | 0.4390 mL | 0.8780 mL | 2.1951 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
hnNOS-IN-3 Related Classifications
HY-W484263 Related Classifications
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