2. Immunology/Inflammation
  3. NO Synthase
  4. hnNOS-IN-3

hnNOS-IN-3 (compound 39) is a selective nNOS inhibitor, with a Ki of 0.32 μM. The nNOS binding of hnNOS-IN-3 is competitive with L-arginine. The selectivity of hnNOS-IN-3 for nNOS versus iNOS (Ki=37 μM) and eNOS (Ki=9.4 μM) is 115-fold and 29-fold, respectively.

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hnNOS-IN-3 Chemical Structure

hnNOS-IN-3 Chemical Structure

CAS No. : 163490-78-6

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hnNOS-IN-3 Related Antibodies

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Description

hnNOS-IN-3 (compound 39) is a selective nNOS inhibitor, with a Ki of 0.32 μM. The nNOS binding of hnNOS-IN-3 is competitive with L-arginine. The selectivity of hnNOS-IN-3 for nNOS versus iNOS (Ki=37 μM) and eNOS (Ki=9.4 μM) is 115-fold and 29-fold, respectively[1].

IC50 & Target

nNOS

0.32 μM (Ki)

eNOS

9.4 μM (Ki)

iNOS

37 μM (Ki)

Molecular Weight

284.73

Formula

C10H12ClF3N2S
CAS No.
SMILES

N=C(SCC)NC1=CC=C(C(F)(F)F)C=C1.[H]Cl
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Room temperature in continental US; may vary elsewhere.
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Purity & Documentation
References
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hnNOS-IN-3 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

hnNOS-IN-3163490-78-6NO SynthaseNitric oxide synthasesNOSInhibitorinhibitorinhibit

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