1637735-84-2

FIIN-3 Chemical Structure
1637735-84-2

Chemical Structure

FIIN-3

  • CAS No.: 1637735-84-2
  • Formula:C34H36Cl2N8O4
  • Molecular Weight:691.61

IUPAC Name: N-(4-((3-(2,6-dichloro-3,5-dimethoxyphenyl)-1-(6-((4-(4-methylpiperazin-1-yl)phenyl)amino)pyrimidin-4-yl)ureido)methyl)phenyl)acrylamide

InChIKey: SFLKJNSBBVSPFE-UHFFFAOYSA-N

SMILES: C=CC(NC1=CC=C(CN(C(NC2=C(Cl)C(OC)=CC(OC)=C2Cl)=O)C3=NC=NC(NC4=CC=C(N5CCN(C)CC5)C=C4)=C3)C=C1)=O

Biological Activity: FIIN-3 is an irreversible inhibitor of FGFR with an IC50 of 13.1, 21, 31.4, and 35.3 nM for FGFR1, FGFR2, FGFR3 and FGFR4, respectively.

Cat. No. Product Name Purity Description Pricing
HY-18603 		FIIN-3 99.01% FIIN-3 is an irreversible inhibitor of FGFR with an IC50 of 13.1, 21, 31.4, and 35.3 nM for FGFR1, FGFR2, FGFR3 and FGFR4, respectively.
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