1643570-24-4
1643570-24-4
Chemical Structure
Elsubrutinib
Synonym(s): ABBV-105
- CAS No.: 1643570-24-4
- Formula:C17H19N3O2
- Molecular Weight:297.35
IUPAC Name: (S)-4-(1-acryloylpiperidin-3-yl)-1H-indole-7-carboxamide
InChIKey: UNHZLHSLZZWMNP-LLVKDONJSA-N
SMILES: O=C(C1=CC=C([C@H]2CN(C(C=C)=O)CCC2)C3=C1NC=C3)N
Biological Activity: Elsubrutinib (ABBV-105) is an orally active, potent, selective and irreversible Bruton's tyrosine kinase (BTK) inhibitor. The IC50 of Elsubrutinib for BTK catalytic domain is 0.18 μM. Elsubrutinib can be used for the research of inflammatory disease[1].
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Elsubrutinib | 98.0% | Elsubrutinib (ABBV-105) is an orally active, potent, selective and irreversible Bruton's tyrosine kinase (BTK) inhibitor. The IC50 of Elsubrutinib for BTK catalytic domain is 0.18 μM. Elsubrutinib can be used for the research of inflammatory disease. | ||||||||||||||||||||
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Elsubrutinib (Standard) | ≥98% | Elsubrutinib (Standard) is the analytical standard of Elsubrutinib (HY-109143). This product is intended for research and analytical applications. Elsubrutinib (ABBV-105) is an orally active, potent, selective and irreversible Bruton's tyrosine Kinase (BTK) inhibitor. The IC50 of Elsubrutinib for BTK catalytic domain is 0.18 μM. Elsubrutinib can be used for the research of inflammatory disease. | ||||||||||||||||||||
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References
Keywords
