1649473-91-5
Chemical Structure
Antibacterial agent 219
- CAS No.: 1649473-91-5
- Formula:C22H14FN3O2
- Molecular Weight:371.36
IUPAC Name: 3-(4-(4-fluorophenoxy)phenyl)-5-(1H-indol-5-yl)-1,2,4-oxadiazole
InChIKey: LJMUZZUGHRTIJT-UHFFFAOYSA-N
SMILES: FC1=CC=C(C=C1)OC2=CC=C(C3=NOC(C4=CC5=C(NC=C5)C=C4)=N3)C=C2
Biological Activity: Antibacterial agent 219 (Compound 2/75c) exhibits antibacterial activity by targeting cell wall biosynthesis. Antibacterial agent 219 inhibits methicillin-resistant Staphylococcus aureus (MRSA) strains (MIC=0.5-32 µg/mL), Enterococcus faecium (MIC=2 µg/mL) and S. aureus (MIC=2 µg/mL)[1][2].
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Antibacterial agent 219 | Antibacterial agent 219 (Compound 2/75c) exhibits antibacterial activity by targeting cell wall biosynthesis. Antibacterial agent 219 inhibits methicillin-resistant Staphylococcus aureus (MRSA) strains (MIC=0.5-32 µg/mL), Enterococcus faecium (MIC=2 µg/mL) and S. aureus (MIC=2 µg/mL). | |||||||||||||||||||||
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Keywords