168482-80-2
Chemical Structure
Oscillamide Y
- CAS No.: 168482-80-2
- Formula:C45H59N7O10
- Molecular Weight:857.99
IUPAC Name: (((3S,6S,9S,12S,15R)-3-benzyl-12-((R)-sec-butyl)-9-(4-hydroxyphenethyl)-6,7-dimethyl-2,5,8,11,14-pentaoxo-1,4,7,10,13-pentaazacyclononadecan-15-yl)carbamoyl)-L-tyrosine
InChIKey: KCAKUFQSCADGHZ-JNFDXLRCSA-N
SMILES: OC(C=C1)=CC=C1CC[C@@H]2NC([C@](NC([C@@H](CCCCNC([C@@H](NC([C@@H](N(C2=O)C)C)=O)CC3=CC=CC=C3)=O)NC(N[C@H](C(O)=O)CC4=CC=C(C=C4)O)=O)=O)([H])[C@H](C)CC)=O
Biological Activity: Oscillamide Y (Compound 1), a ureido-containing cyclic peptide, is a Chymotrypsin inhibitor. Oscillamide Y can be isolated from freshwater toxic cyanobacterium Oscillatoria agardhii. Oscillamide Y has potent toxicity against fish, daphnid magna and algae with a stimulatory effect for Raphidocelis subcapitata (EC50: 4.62 mg/L). Oscillamide Y induces high luminescence inhibition in Aliivibrio fischeri. Oscillamide Y can be used for ecological development research[1][2].
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Oscillamide Y | Oscillamide Y (Compound 1), a ureido-containing cyclic peptide, is a Chymotrypsin inhibitor. Oscillamide Y can be isolated from freshwater toxic cyanobacterium Oscillatoria agardhii. Oscillamide Y has potent toxicity against fish, daphnid magna and algae with a stimulatory effect for Raphidocelis subcapitata (EC50: 4.62 mg/L). Oscillamide Y induces high luminescence inhibition in Aliivibrio fischeri. Oscillamide Y can be used for ecological development research. | |||||||||||||||||||||
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References
- [1]. Sano T, et al. Oscillamide Y, a chymotrypsin inhibitor from toxic Oscillatoria agardhii[J]. Tetrahedron Letters, 1995, 36(33): 5933-5936.
- [2]. Zorrilla JG, et al. Ecotoxicological assessment of cyclic peptides produced by a Planktothrix rubescens bloom: Impact on aquatic model organisms. Environ Res. 2024 Sep 15;257:119394. [Content Brief]
