168701-80-2
168701-80-2
Chemical Structure
8-Nitroguanine
- CAS 番号: 168701-80-2
- Formula:C5H4N6O3
- Molecular Weight:196.12
IUPAC Name: 2-amino-8-nitro-3,7-dihydro-6H-purin-6-one
InChIKey: IYHJRKNFFYAOGE-UHFFFAOYSA-N
SMILES: O=C1N=C(N)NC2=C1NC([N+]([O-])=O)=N2
Biological Activity: 8-Nitroguanine, a product of nitrative DNA damage caused by reactive nitrogen species, is a potential biomarker for progression of malignant fibrous histiocytoma[1][2].
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8-Nitroguanine | 8-Nitroguanine, a product of nitrative DNA damage caused by reactive nitrogen species, is a potential biomarker for progression of malignant fibrous histiocytoma. | |||||||||||||||||||||
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References
- [1]. Hiroshi Ohshima, et al. 8-nitroguanine, a product of nitrative DNA damage caused by reactive nitrogen species: formation, occurrence, and implications in inflammation and carcinogenesis. Antioxid Redox Signal. 2006 May-Jun;8(5-6):1033-45. [Content Brief]
- [2]. Yoko Hoki, et al. 8-Nitroguanine as a potential biomarker for progression of malignant fibrous histiocytoma, a model of inflammation-related cancer. Oncol Rep. 2007 Nov;18(5):1165-9. [Content Brief]
Keywords
