169474-77-5
Chemical Structure
FCE 28654
- CAS No.: 169474-77-5
- Formula:C25H35N2O7P
- Molecular Weight:506.53
IUPAC Name: 4-((4R,5R)-2-((3-(2,6-diisopropylphenyl)ureido)methyl)-4,5-dimethyl-1,3-dioxolan-2-yl)phenyl dihydrogen phosphate
InChIKey: WUEHURHTEPWPPO-QZTJIDSGSA-N
SMILES: CC(C)C(C=CC=C1C(C)C)=C1NC(NCC2(C3=CC=C(OP(O)(O)=O)C=C3)O[C@H](C)[C@@H](C)O2)=O
Biological Activity: FCE 28654 is an inhibitor of acylCoA: cholesterol acyltransferase (ACAT), weakly inhibiting ACAT in microsomes from rabbit aorta and intestine, and monkey liver, with IC50s of 2.55, 1.08 and 5.69 μM, respcetively.
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FCE 28654 | FCE 28654 is an inhibitor of acylCoA: cholesterol acyltransferase (ACAT), weakly inhibiting ACAT in microsomes from rabbit aorta and intestine, and monkey liver, with IC50s of 2.55, 1.08 and 5.69 μM, respcetively. | |||||||||||||||||||||
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Keywords