170230-39-4
170230-39-4
Chemical Structure
SB-216641
- CAS No.: 170230-39-4
- Formula:C28H30N4O4
- Molecular Weight:486.56
InChIKey: JRNUKVFYILMMLX-UHFFFAOYSA-N
SMILES: O=C(C1=CC=C(C2=C(C)C=C(C3=NOC(C)=N3)C=C2)C=C1)NC4=CC=C(C(OCCN(C)C)=C4)OC
Biological Activity: SB-216641 is a selective 5-HT1b antagonist. SB-216641 mildly prevents stress-induced behavioral performance dysregulations[1][2].
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SB-216641 | SB-216641 is a selective 5-HT1b antagonist. SB-216641 mildly prevents stress-induced behavioral performance dysregulations. | |||||||||||||||||||||
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References
- [1]. Taylor R M, et al. Systemic Administration of the 5-HT1b Antagonist SB-216641 Prior to Acute Stress Exposure in Rats Mildly Prevents Stress-induced Behavioral Performance Dysregulations[J]. The Journal of Pharmacology and Experimental Therapeutics, 2024, 389: 115.
- [2]. Price GW, et al. SB-216641 and BRL-15572--compounds to pharmacologically discriminate h5-HT1B and h5-HT1D receptors. Naunyn Schmiedebergs Arch Pharmacol. 1997 Sep;356(3):312-20. [Content Brief]
Keywords
