1708978-54-4
1708978-54-4
Chemical Structure
TP-α
Synonym(s): TPG-456
- CAS No.: 1708978-54-4
- Formula:C38H51N3O2
- Molecular Weight:581.83
InChIKey: FTVRCKFCBSPJSD-UHFFFAOYSA-N
SMILES: CC(C1=CC2=C(C3(CCCC(CN(C(CN(C)C4=CC5=CC=C(C=C5C=C4)C(C)=O)=O)CCCN)(C3CC2)C)C)C=C1)C
Biological Activity: TP-α (TPG-456) is a glucagon-selective two-photon fluorescent probe with a Kd of 65 μM. TP-α directly interacts with glucagon to produce significant fluorescence enhancement. TP-α selectively stains viable glucagon-secreting α cells in pancreatic islets, enabling visualization of their localization, distribution and availability. TP-α is applicable to diabetes research (Ex/Em = 370nm/510 nm)[1].
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TP-α | TP-α (TPG-456) is a glucagon-selective two-photon fluorescent probe with a Kd of 65 μM. TP-α directly interacts with glucagon to produce significant fluorescence enhancement. TP-α selectively stains viable glucagon-secreting α cells in pancreatic islets, enabling visualization of their localization, distribution and availability. TP-α is applicable to diabetes research (Ex/Em = 370nm/510 nm). | |||||||||||||||||||||
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