172544-75-1
Chemical Structure
KY 234
- CAS No.: 172544-75-1
- Formula:C33H34N5NaO2
- Molecular Weight:555.65
IUPAC Name: sodium 3-((1H-imidazol-1-yl)methyl)-1-(3-(4-benzhydrylpiperazin-1-yl)propyl)-1H-indole-6-carboxylate
InChIKey: NARCUGWOEJABQC-UHFFFAOYSA-M
SMILES: O=C(C1=CC2=C(C=C1)C(CN3C=CN=C3)=CN2CCCN4CCN(C(C5=CC=CC=C5)C6=CC=CC=C6)CC4)O[Na]
Biological Activity: KY 234 is an orally effective inhibitor that targets thromboxane A2 production, with an IC50 of 5 μM. KY 234 significantly inhibits leukotriene D4 (LTD4), histamine, and antigen-induced bronchoconstriction in guinea pigs, with IC50 values of 6.0 mg/kg, 2.5 mg/kg, and 6.3 mg/kg, respectively[1].
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KY 234 | KY 234 is an orally effective inhibitor that targets thromboxane A2 production, with an IC50 of 5 μM. KY 234 significantly inhibits leukotriene D4 (LTD4), histamine, and antigen-induced bronchoconstriction in guinea pigs, with IC50 values of 6.0 mg/kg, 2.5 mg/kg, and 6.3 mg/kg, respectively. | |||||||||||||||||||||
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Keywords
