173458-56-5
173458-56-5
Chemical Structure
CGP-59326
Synonym(s): TRX-13
- CAS No.: 173458-56-5
- Formula:C14H13ClN4
- Molecular Weight:272.73
IUPAC Name: N-(3-chlorophenyl)-5,6-dimethyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine
InChIKey: WXJDWBDGDSXEFA-UHFFFAOYSA-N
SMILES: ClC1=CC=CC(NC2=NC=NC3=C2C(C)=C(C)N3)=C1
Biological Activity: CGP-59326 (TRX-13) is a highly potent and selective epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (IC50=0.027 μM). CGP-59326 blocks the EGFR signaling pathwa, demonstrating highly selective inhibition of EGFR-dependent tumor cells. CGP-59326 is promising for research of cancers[1].
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CGP-59326 | CGP-59326 (TRX-13) is a highly potent and selective epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (IC50=0.027 μM). CGP-59326 blocks the EGFR signaling pathwa, demonstrating highly selective inhibition of EGFR-dependent tumor cells. CGP-59326 is promising for research of cancers. | |||||||||||||||||||||
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References
Keywords
