17402-86-7
17402-86-7
Chemical Structure
PHGDH-IN-5
- CAS. Nr.: 17402-86-7
- Formula:C8H5NO4S
- Molecular Weight:211.19
InChIKey: LWKOZDAODXAJCF-UHFFFAOYSA-N
SMILES: O=S1(C2=CC=CC([N+]([O-])=O)=C2C=C1)=O
Biological Activity: PHGDH-IN-5 (Compound B12) is a covalen inhibitor of PHGDH with an IC50 value of 0.29 μM. PHGDH-IN-5 can inhibit cell proliferation in cancer cell lines overexpressing PHGDH. PHGDH-IN-5 can reduce the production of serine derived from glucose in MDA-MB-468 cells[1].
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PHGDH-IN-5 | 98.12% | PHGDH-IN-5 (Compound B12) is a covalen inhibitor of PHGDH with an IC50 value of 0.29 μM. PHGDH-IN-5 can inhibit cell proliferation in cancer cell lines overexpressing PHGDH. PHGDH-IN-5 can reduce the production of serine derived from glucose in MDA-MB-468 cells. | ||||||||||||||||||||
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