177602-12-9
Chemical Structure
Vaccarin C
- CAS No.: 177602-12-9
- Formula:C43H56N8O8
- Molecular Weight:812.95
InChIKey: PFLNHBDSHKCNNW-OPGKZIRUSA-N
SMILES: O=C(N1[C@@](C(NCC(N[C@H](C(N[C@H](C(N2[C@](CCC2)([H])C(N[C@H](C(N3)=O)CC(C)C)=O)=O)C(C)C)=O)CC4=CC=C(C=C4)O)=O)=O)([H])CCC1)[C@@H]3CC5=CNC6=CC=CC=C56
Biological Activity: Vaccarin C (Compound VIII) is a cycloheptapeptide with good antifungal activity against pathogenic fungi and dermatophytes M. audouinii and T. mentagrophytes with MIC values of 6 µg/mL. Vaccarin C also has high cytotoxicity against Dalton's lymphoma ascites (DLA) and Ehrlich's ascites carcinoma (EAC) cell lines with IC50 values of 3.35 and 5.72 μM, respectively[1].
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Vaccarin C | Vaccarin C (Compound VIII) is a cycloheptapeptide with good antifungal activity against pathogenic fungi and dermatophytes M. audouinii and T. mentagrophytes with MIC values of 6 µg/mL. Vaccarin C also has high cytotoxicity against Dalton's lymphoma ascites (DLA) and Ehrlich's ascites carcinoma (EAC) cell lines with IC50 values of 3.35 and 5.72 μM, respectively. | |||||||||||||||||||||
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