1778682-60-2
Chemical Structure
QND8
- CAS. Nr.: 1778682-60-2
- Formula:C15H18N4O
- Molecular Weight:270.33
InChIKey: ZRCMYKLGYHVJGO-UHFFFAOYSA-N
SMILES: OC1=CC=C(C2=CN(C3[C@H]4CC[N@](CC4)C3)N=N2)C=C1
Biological Activity: QND8 is a selective and potent α7 nicotinic acetylcholine receptor (nAChR) agonist. QND8 can alleviate thermal hyperalgesia and mechanical hyperalgesia in carrageenan-induced inflammatory pain mouse model. QND8 can reduce the swelling of the mice feet, inhibit the release of pro-inflammatory factors at the inflammatory site, and prevent the infiltration of white blood cells. QND8 can be used for the research of inflammation and neurological disease, such as arthritis[1].
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QND8 | QND8 is a selective and potent α7 nicotinic acetylcholine receptor (nAChR) agonist. QND8 can alleviate thermal hyperalgesia and mechanical hyperalgesia in carrageenan-induced inflammatory pain mouse model. QND8 can reduce the swelling of the mice feet, inhibit the release of pro-inflammatory factors at the inflammatory site, and prevent the infiltration of white blood cells. QND8 can be used for the research of inflammation and neurological disease, such as arthritis. | |||||||||||||||||||||
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