178765-54-3
178765-54-3
Chemical Structure
3-Hydroxybakuchiol
- CAS No.: 178765-54-3
- Formula:C18H24O2
- Molecular Weight:272.38
IUPAC Name: (S,E)-4-(3,7-dimethyl-3-vinylocta-1,6-dien-1-yl)benzene-1,2-diol
InChIKey: ZHKCOGVKHHAUBK-NCUBBLFSSA-N
SMILES: OC1=CC=C(/C=C/[C@](C)(C=C)CC/C=C(C)\C)C=C1O
Biological Activity: 3-Hydroxybakuchiol can be isolated from Otholobium mexicanum J. W. Grimes. 3-Hydroxybakuchiol is an electron transport chain (ETC) inhibitor. 3-Hydroxybakuchiol has antitumor activity, and induces tumor cell apoptosis. 3-Hydroxybakuchiol also has moderate inhibitory activity against α-glucosidase (IC50: 345 μM)[1][2].
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3-Hydroxybakuchiol | 3-Hydroxybakuchiol can be isolated from Otholobium mexicanum J. W. Grimes. 3-Hydroxybakuchiol is an electron transport chain (ETC) inhibitor. 3-Hydroxybakuchiol has antitumor activity, and induces tumor cell apoptosis. 3-Hydroxybakuchiol also has moderate inhibitory activity against α-glucosidase (IC50: 345 μM). | |||||||||||||||||||||
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References
- [1]. Jaña F, et al. Tumor cell death induced by the inhibition of mitochondrial electron transport: the effect of 3-hydroxybakuchiol. Toxicol Appl Pharmacol. 2013 Oct 15;272(2):356-64. [Content Brief]
- [2]. Suárez AI, et al. Main Constituents and Antidiabetic Properties of Otholobium mexicanum. Nat Prod Commun. 2017 Apr;12(4):533-535. [Content Brief]
