179030-22-9
179030-22-9
Chemical Structure
NAG-thiazoline
- CAS No.: 179030-22-9
- Formula:C8H13NO4S
- Molecular Weight:219.26
IUPAC Name: (3aR,5R,6S,7R,7aR)-5-(hydroxymethyl)-2-methyl-3a,6,7,7a-tetrahydro-5H-pyrano[3,2-d]thiazole-6,7-diol
InChIKey: DRHXTSWSUAJOJZ-FMDGEEDCSA-N
SMILES: O[C@@H]1[C@]2([H])[C@](SC(C)=N2)([H])O[C@@H]([C@H]1O)CO
Biological Activity: NAG-thiazoline is a O-GlcNAcase inhibitor with a Ki of 180 nM. NAG-thiazoline is a potent GH20 GlcNAcase (VhGlcNAcase) inhibitor with an IC50 of 11.9 μM and a Ki of 62 µM[1].
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NAG-thiazoline | NAG-thiazoline is a O-GlcNAcase inhibitor with a Ki of 180 nM. NAG-thiazoline is a potent GH20 GlcNAcase (VhGlcNAcase) inhibitor with an IC50 of 11.9 μM and a Ki of 62 µM. | |||||||||||||||||||||
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References
Keywords
