179479-04-0
Chemical Structure
3’-O-Me-G(iBu)-2’-phosphoramidite
- CAS No.: 179479-04-0
- Formula:C45H56N7O9P
- Molecular Weight:869.94
IUPAC Name: (2R,3R,4R,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-methoxy-2-(6-oxo-2-propionamido-1,6-dihydro-9H-purin-9-yl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
InChIKey: POYXHFZLQWXZTI-MLLDKZSOSA-N
SMILES: O=C1C2=C(N([C@H]3[C@H](OP(N(C(C)C)C(C)C)OCCC#N)[C@H](OC)[C@@H](COC(C4=CC=C(OC)C=C4)(C5=CC=C(OC)C=C5)C6=CC=CC=C6)O3)C=N2)NC(NC(C(C)C)=O)=N1
Biological Activity: 3’-O-Me-G(iBu)-2’-phosphoramidite is a guanosine analog. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7)[1].
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3’-O-Me-G(iBu)-2’-phosphoramidite | 95.0% | 3’-O-Me-G(iBu)-2’-phosphoramidite is a guanosine analog. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7). | ||||||||||||||||||||
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Keywords
