1807873-14-8
1807873-14-8
Chemical Structure
KSI-6666
- CAS 番号: 1807873-14-8
- Formula:C23H26ClF3N2O2
- Molecular Weight:454.91
InChIKey: CEBVCUSXXIVBGX-UHFFFAOYSA-N
SMILES: CCN(C(C1=CC=C(C(CN2CC(C2)C(O)=O)=C1)C)C)C3=CC=C(C(C(F)(F)F)=C3)Cl
Biological Activity: KSI-6666 is an orally active, competitive antagonist for sphingosine 1-phosphate receptor 1 (S1PR1), with an IC50 of 6.4 nM. KSI-6666 exhibits anti-inflammatory efficacy in autoimmune encephalomyelitis model and T cell transfer colitis model[1].
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KSI-6666 | 96.15% | KSI-6666 is an orally active, competitive antagonist for sphingosine 1-phosphate receptor 1 (S1PR1), with an IC50 of 6.4 nM. KSI-6666 exhibits anti-inflammatory efficacy in autoimmune encephalomyelitis model and T cell transfer colitis model. | ||||||||||||||||||||
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