1808258-99-2
1808258-99-2
Chemical Structure
BMS-986172
- CAS No.: 1808258-99-2
- Formula:C24H22F7N7O3
- Molecular Weight:589.47
InChIKey: VFFPVFKSCNJAMO-QFIPXVFZSA-N
SMILES: FC1=C([C@]2(C(F)(F)F)CC(C3=NN(C=C3)CC4CC4)=C(C(N2)=O)N5N=NNC5=O)C=CC(OCCCC(F)(F)F)=C1
Biological Activity: BMS-986172 is an orally active and selective Monoacylglycerol acyltransferase 2 (MGAT2) inhibitor with an IC50 of 4.6 nM and 20 nM for hMGAT2 and mMGAT2, respectively. BMS-986172 reduces food intake and body weight. BMS-986172 can be used for the researches of metabolic diseases, such as obesity [1].
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BMS-986172 | 99.48% | BMS-986172 is an orally active and selective Monoacylglycerol acyltransferase 2 (MGAT2) inhibitor with an IC50 of 4.6 nM and 20 nM for hMGAT2 and mMGAT2, respectively. BMS-986172 reduces food intake and body weight. BMS-986172 can be used for the researches of metabolic diseases, such as obesity . | ||||||||||||||||||||
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References
Keywords
