180869-17-4
180869-17-4
Chemical Structure
p38 MAPK-IN-9
- CAS No.: 180869-17-4
- Formula:C21H25FN6
- Molecular Weight:380.46
SMILES: FC1=CC=C(C2=C(C3=CC=NC(NCC)=N3)N(C4CCN(CC4)C)C=N2)C=C1
Biological Activity: p38 MAPK-IN-9 (Compound 15) is an orally active and highly selective p38α mitogen-activated protein kinase (p38 MAPK) inhibitor with an IC50 value of 9.6 nM. p38 MAPK-IN-9 is promising for research of inflammatory diseases such as rheumatoid arthritis, septic shock, and chronic obstructive pulmonary disease (COPD)[1].
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p38 MAPK-IN-9 | p38 MAPK-IN-9 (Compound 15) is an orally active and highly selective p38α mitogen-activated protein kinase (p38 MAPK) inhibitor with an IC50 value of 9.6 nM. p38 MAPK-IN-9 is promising for research of inflammatory diseases such as rheumatoid arthritis, septic shock, and chronic obstructive pulmonary disease (COPD). | |||||||||||||||||||||
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Keywords
