1809413-98-6
1809413-98-6
Chemical Structure
Wnt/β-catenin-IN-3
- CAS No.: 1809413-98-6
- Formula:C26H23NO7
- Molecular Weight:461.46
InChIKey: XSLDGSUTFJJGRI-UHFFFAOYSA-N
SMILES: COC1=CC=C(C=C1)C(NC2=CC(C3=CC(C4=C(C(OC)=C(C=C4O3)OC)OC)=O)=CC=C2)=O
Biological Activity: Wnt/β-catenin-IN-3 (compound 17) is a Wnt/β-catenin inhibitor with low micromolarGI50s against various cancer cells. Wnt/β-catenin-IN-3triggers G2/M cell cycle arrest though activation of p53-p21 pathway as well as intrinsic and extrinsic apoptotic death of colon cancer cells[1].
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Wnt/β-catenin-IN-3 | Wnt/β-catenin-IN-3 (compound 17) is a Wnt/β-catenin inhibitor with low micromolarGI50s against various cancer cells. Wnt/β-catenin-IN-3triggers G2/M cell cycle arrest though activation of p53-p21 pathway as well as intrinsic and extrinsic apoptotic death of colon cancer cells. | |||||||||||||||||||||
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References
Keywords
