Wnt/β-catenin-IN-3
Wnt/β-catenin-IN-3 (compound 17) is a Wnt/β-catenin inhibitor with low micromolarGI50s against various cancer cells. Wnt/β-catenin-IN-3triggers G2/M cell cycle arrest though activation of p53-p21 pathway as well as intrinsic and extrinsic apoptotic death of colon cancer cells.
For research use only. We do not sell to patients.
- CAS No.: 1809413-98-6
- Formula: C26H23NO7
- Molecular Weight:461.46
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HepG2 | GI50 |
22.2 μM
Compound: 5m
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Growth inhibition of human HepG2 cells by MTT assay
Growth inhibition of human HepG2 cells by MTT assay
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[PMID: 27503682] |
| MCF7 | GI50 |
6.87 μM
Compound: 5m
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Growth inhibition of human MCF7 cells by MTT assay
Growth inhibition of human MCF7 cells by MTT assay
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[PMID: 27503682] |
Chemical Information
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CAS No. 1809413-98-6
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Molecular Weight 461.46
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Formula C26H23NO7
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SMILES
COC1=CC=C(C=C1)C(NC2=CC(C3=CC(C4=C(C(OC)=C(C=C4O3)OC)OC)=O)=CC=C2)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Wnt/β-catenin-IN-3 Related Classifications
HY-158210 Related Classifications
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