181125-92-8

AF40431 Chemical Structure
181125-92-8

Chemical Structure

AF40431

  • CAS No.: 181125-92-8
  • Formula:C17H21NO5
  • Molecular Weight:319.35

IUPAC Name: ((7-hydroxy-4-methyl-2-oxo-2H-chromen-8-yl)methyl)-L-leucine

InChIKey: YPJLUCAXHFPZJD-ZDUSSCGKSA-N

SMILES: CC(C)C[C@@H](C(O)=O)NCC1=C(O2)C(C(C)=CC2=O)=CC=C1O

Biological Activity: AF40431, the first reported small-molecule ligand of sortilin, has an IC50 of 4.4 µM and a Kd of 0.7 µM . AF40431 is bound in the neurotensin-binding site of sortilin[1].

Cat. No. Product Name Purity Description Pricing
HY-124673
AF40431 98.09% AF40431, the first reported small-molecule ligand of sortilin, has an IC50 of 4.4 µM and a Kd of 0.7 µM . AF40431 is bound in the neurotensin-binding site of sortilin.
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