181125-92-8

AF40431 Chemical Structure
181125-92-8

Chemical Structure

AF40431

  • CAS No.: 181125-92-8
  • Formula:C17H21NO5
  • Molecular Weight:319.35

IUPAC Name: ((7-hydroxy-4-methyl-2-oxo-2H-chromen-8-yl)methyl)-L-leucine

InChIKey: YPJLUCAXHFPZJD-ZDUSSCGKSA-N

SMILES: CC(C)C[C@@H](C(O)=O)NCC1=C(O2)C(C(C)=CC2=O)=CC=C1O

Biological Activity: AF40431, the first reported small-molecule ligand of sortilin, has an IC50 of 4.4 µM and a Kd of 0.7 µM . AF40431 is bound in the neurotensin-binding site of sortilin[1].

Cat. No. Product Name Purity Description Pricing
HY-124673
AF40431 98.09% AF40431, the first reported small-molecule ligand of sortilin, has an IC50 of 4.4 µM and a Kd of 0.7 µM . AF40431 is bound in the neurotensin-binding site of sortilin.
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This product is a controlled substance and not for sale in your territory.

This product is not for sale in your territory.

This compound is listed in the SVHC (Substances of Very High Concern) candidate list of ECHA (European Chemicals Agency).

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References