1818427-07-4
1818427-07-4
Chemical Structure
CDK8/19-IN-1
- CAS No.: 1818427-07-4
- Formula:C19H18N4O4S2
- Molecular Weight:430.50
IUPAC Name: 8-((6-((2-methoxyethyl)carbamoyl)pyridin-3-yl)oxy)-4,5-dihydrothieno[3',4':3,4]benzo[1,2-d]isothiazole-6-carboxamide
InChIKey: NENJFZKQHYXRDQ-UHFFFAOYSA-N
SMILES: O=C(C1=C2CCC3=C(SN=C3)C2=C(OC4=CC=C(C(NCCOC)=O)N=C4)S1)N
Biological Activity: CDK8/19-IN-1 is a potent, selective and oral bioavailable CDK8/19 dual inhibitor, with IC50s of 0.46 nM, 0.99 nM and 270 nM for CDK8, CDK19 and CDK9, respectively.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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CDK8/19-IN-1 | 98.08% | CDK8/19-IN-1 is a potent, selective and oral bioavailable CDK8/19 dual inhibitor, with IC50s of 0.46 nM, 0.99 nM and 270 nM for CDK8, CDK19 and CDK9, respectively. | ||||||||||||||||||||
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CDK8/19-IN-1 (Standard) | ≥98% | CDK8/19-IN-1 (Standard) is the analytical standard of CDK8/19-IN-1 (HY-111427). This product is intended for research and analytical applications. CDK8/19-IN-1 is a potent, selective and oral bioavailable CDK8/19 dual inhibitor, with IC50s of 0.46 nM, 0.99 nM and 270 nM for CDK8, CDK19 and CDK9, respectively. | ||||||||||||||||||||
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