1821107-98-5
1821107-98-5
Chemical Structure
DNS-8254
- CAS No.: 1821107-98-5
- Formula:C18H15BrF3N5O
- Molecular Weight:454.24
IUPAC Name: (S)-(3-bromo-4-fluorophenyl)(3,3-difluoro-5-(5-methyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl)piperidin-1-yl)methanone
InChIKey: TTWAYHJJEHLVNR-LBPRGKRZSA-N
SMILES: O=C(C1=CC=C(F)C(Br)=C1)N2CC(F)(F)C[C@H](C3=CC(C)=NC4=NC=NN34)C2
Biological Activity: DNS-8254 is an oral active and brain-penetrating PDE2a inhibitor with the IC50 of 8 nM. DNS-8254 shows memory enhancing effects in a rat model[1].
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DNS-8254 | DNS-8254 is an oral active and brain-penetrating PDE2a inhibitor with the IC50 of 8 nM. DNS-8254 shows memory enhancing effects in a rat model. | |||||||||||||||||||||
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References
Keywords
