182261-96-7
182261-96-7
Chemical Structure
Clausine K
- CAS No.: 182261-96-7
- Formula:C15H13NO4
- Molecular Weight:271.27
InChIKey: LDKCHJXUOLZQQV-UHFFFAOYSA-N
SMILES: O=C(C1=C(OC)C=C(NC2=C3C=CC(OC)=C2)C3=C1)O
Biological Activity: Clausine K is a carbazole alkaloid anticancer agent. Clausine K exhibits strong cytotoxicity against human hepatoma HepG2 cells (IC50 = 1.05 μg/mL), superior to the standard drug Etoposide (HY-13629) (IC50 13.40 μg/mL). Clausine K can be naturally extracted from the dried stems of Clausena excavata (a plant of the Rutaceae family) through chromatographic separation and other methods[1].
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Clausine K | Clausine K is a carbazole alkaloid anticancer agent. Clausine K exhibits strong cytotoxicity against human hepatoma HepG2 cells (IC50 = 1.05 μg/mL), superior to the standard drug Etoposide (HY-13629) (IC50 13.40 μg/mL). Clausine K can be naturally extracted from the dried stems of Clausena excavata (a plant of the Rutaceae family) through chromatographic separation and other methods. | |||||||||||||||||||||
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References
Keywords
