1824708-03-3
1824708-03-3
Chemical Structure
Smurf1-IN-1
- CAS No.: 1824708-03-3
- Formula:C24H29ClN6O2
- Molecular Weight:468.98
InChIKey: DJCHYTWZRDUVHQ-UHFFFAOYSA-N
SMILES: O=C(C1=C(C)N(C2=CC=C(C3CC3)C=C2Cl)N=N1)NC4=C(C)N(C)N(C5CCCCC5)C4=O
Biological Activity: Smurf1-IN-1 is an orally active and selective inhibitor of specific E3 ubiquitin protein ligase 1 (SMURF1) with an IC50 of 92 nM. Smurf1-IN-1 has significant efficacy in rats model of pulmonary hypertension[1].
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Smurf1-IN-1 | 99.47% | Smurf1-IN-1 is an orally active and selective inhibitor of specific E3 ubiquitin protein ligase 1 (SMURF1) with an IC50 of 92 nM. Smurf1-IN-1 has significant efficacy in rats model of pulmonary hypertension. | ||||||||||||||||||||
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References
Keywords
