183500-36-9
183500-36-9
Chemical Structure
CYP19A1/CYP11B2-IN-1
- CAS No.: 183500-36-9
- Formula:C12H11N3O
- Molecular Weight:213.24
InChIKey: ACFSBQWDVYWNRT-UHFFFAOYSA-N
SMILES: N#CC1=CC=C(CN2C=NC=C2CO)C=C1
Biological Activity: CYP19A1/CYP11B2-IN-1 (Compound X21) is a potent and selective aromatase and aldosterone synthase dual inhibitor with IC50s of 2.3 nM and 29 nM for aromatase (CYP19A1) and aldosterone synthase (CYP11B2), respectively. CYP19A1/CYP11B2-IN-1 has excellent antiproliferative and pro-apoptotic activity against the cancer cell. CYP19A1/CYP11B2-IN-1 can be used for research of breast cancer[1].
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CYP19A1/CYP11B2-IN-1 | 99.85% | CYP19A1/CYP11B2-IN-1 (Compound X21) is a potent and selective aromatase and aldosterone synthase dual inhibitor with IC50s of 2.3 nM and 29 nM for aromatase (CYP19A1) and aldosterone synthase (CYP11B2), respectively. CYP19A1/CYP11B2-IN-1 has excellent antiproliferative and pro-apoptotic activity against the cancer cell. CYP19A1/CYP11B2-IN-1 can be used for research of breast cancer. | ||||||||||||||||||||
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References
Keywords
