1853982-41-8
Chemical Structure
GPR40 agonist 1
- CAS No.: 1853982-41-8
- Formula:C27H30FN3O4
- Molecular Weight:479.54
IUPAC Name: (S)-3-cyclopropyl-3-(3-((5-(5-fluoro-2-methoxypyridin-4-yl)-6-isobutylpyrazin-2-yl)methoxy)phenyl)propanoic acid
InChIKey: FNXMDDKBLZLDDD-NRFANRHFSA-N
SMILES: COC1=NC=C(F)C(C2=C(CC(C)C)N=C(COC3=CC=CC([C@H](C4CC4)CC(O)=O)=C3)C=N2)=C1
Biological Activity: GPR40 agonist 1 is a potent and novel GPR40 full agonist with an EC50 of 2 nM and 17 nM for hGPR40 and rGPR40, respectively.
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GPR40 agonist 1 | GPR40 agonist 1 is a potent and novel GPR40 full agonist with an EC50 of 2 nM and 17 nM for hGPR40 and rGPR40, respectively. | |||||||||||||||||||||
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Keywords