1863905-38-7
1863905-38-7
Chemical Structure
PF-06737007
- CAS No.: 1863905-38-7
- Formula:C25H28F4N2O6
- Molecular Weight:528.49
IUPAC Name: 2-(((3R,4S)-3-fluoro-1-(2-(4-(trifluoromethoxy)phenyl)acetyl)piperidin-4-yl)oxy)-4-(2-hydroxy-2-methylpropoxy)benzamide
InChIKey: AUTGNDRENPBZKA-UXHICEINSA-N
SMILES: O=C(N)C1=CC=C(OCC(C)(O)C)C=C1O[C@@H]2[C@H](F)CN(C(CC3=CC=C(OC(F)(F)F)C=C3)=O)CC2
Biological Activity: PF-06737007 is a potent pan-Trk inhibitor in cell-based assays with IC50s of 7.7 nM, 15 nM and 3.9 nM for TrkA, TrkB and TrkC, respectively[1]. Anti-hyperalgesic effect[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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PF-06737007 | 99.90% | PF-06737007 is a potent pan-Trk inhibitor in cell-based assays with IC50s of 7.7 nM, 15 nM and 3.9 nM for TrkA, TrkB and TrkC, respectively. Anti-hyperalgesic effect. | ||||||||||||||||||||
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References
Keywords
