186752-78-3
Chemical Structure
Olcorolimus
Synonym(s): SAR-943
- CAS No.: 186752-78-3
- Formula:C51H81NO12
- Molecular Weight:900.19
InChIKey: QFMKPDZCOKCBAQ-NFCVMBANSA-N
SMILES: O=C1N2[C@](CCCC2)([H])C(O[C@](CC[C@@H](/C=C([C@H]([C@H](C([C@H](C)C[C@H](C)/C=C/C=C/C=C(C)/[C@@H](OC)C[C@@]3([H])O[C@](O)([C@@H](CC3)C)C1=O)=O)OC)O)\C)C)([H])[C@H](C)C[C@H]4C[C@H]([C@H](O)CC4)OC)=O
Biological Activity: Olcorolimus (SAR-943) is a Rapamycin (HY-10219) derivative. Olcorolimus can reduce IL-4, IL-5, eosinophil, neutrophil, lymphocyte, cellular fibronectin; lung epithelial cell proliferation and mucus hypersecretory phenotype in Ovalbumin (HY-W250978)-sensitized BALB/c mice. Olcorolimus can be used for the researches of inflammation and immunology, such as asthma[1].
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Olcorolimus | Olcorolimus (SAR-943) is a Rapamycin (HY-10219) derivative. Olcorolimus can reduce IL-4, IL-5, eosinophil, neutrophil, lymphocyte, cellular fibronectin; lung epithelial cell proliferation and mucus hypersecretory phenotype in Ovalbumin (HY-W250978)-sensitized BALB/c mice. Olcorolimus can be used for the researches of inflammation and immunology, such as asthma. | |||||||||||||||||||||
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Keywords