1884640-99-6
1884640-99-6
Chemical Structure
NI-42
- CAS No.: 1884640-99-6
- Formula:C18H15N3O3S
- Molecular Weight:353.40
IUPAC Name: 4-cyano-N-(1,3-dimethyl-2-oxo-1,2-dihydroquinolin-6-yl)benzenesulfonamide
InChIKey: BMVCSXFOQPYKKC-UHFFFAOYSA-N
SMILES: O=S(C1=CC=C(C#N)C=C1)(NC2=CC=C(N(C)C(C(C)=C3)=O)C3=C2)=O
Biological Activity: NI-42 (compound 13-d), a structurally orthogonal chemical probe for the BRPFs, is a biased, potent inhibitor of the BRD of the BRPFs (IC50s of BRPF1/2/3=7.9/48/260 nM; Kds of BRPF1/2/3=40/210/940 nM) with excellent selectivity over nonclass IV BRD proteins[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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NI-42 | 99.53% | NI-42 (compound 13-d), a structurally orthogonal chemical probe for the BRPFs, is a biased, potent inhibitor of the BRD of the BRPFs (IC50s of BRPF1/2/3=7.9/48/260 nM; Kds of BRPF1/2/3=40/210/940 nM) with excellent selectivity over nonclass IV BRD proteins. | ||||||||||||||||||||
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NI-42 (Standard) | ≥98% | NI-42 (Standard) is the analytical standard of NI-42 (HY-101121). This product is intended for research and analytical applications. NI-42 (compound 13-d), a structurally orthogonal chemical probe for the BRPFs, is a biased, potent inhibitor of the BRD of the BRPFs (IC50s of BRPF1/2/3=7.9/48/260 nM; Kds of BRPF1/2/3=40/210/940 nM) with excellent selectivity over nonclass IV BRD proteins. | ||||||||||||||||||||
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References
Keywords
