189057-68-9
Chemical Structure
ZINC05626394
- CAS. Nr.: 189057-68-9
- Formula:C11H10N2OS2
- Molecular Weight:250.34
IUPAC Name: 6-((phenylthio)methyl)-2-thioxo-2,3-dihydropyrimidin-4(1H)-one
InChIKey: VNTBGGWDZYETPH-UHFFFAOYSA-N
SMILES: O=C(N1)C=C(NC1=S)CSC2=CC=CC=C2
Biological Activity: ZINC05626394 is a cytochrome b5 reductase 3 inhibitor with activity by increasing nitric oxide bioavailability. ZINC05626394 may have potential applications in anti-cancer suppression, especially in combination with antibody drug conjugates (ADCs) and immune checkpoint inhibitors. The efficacy of ZINC05626394 may be limited by different mechanisms, including antigen-related resistance and failure of endocytosis[1].
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ZINC05626394 | 99.8% | ZINC05626394 is a cytochrome b5 reductase 3 inhibitor with activity by increasing nitric oxide bioavailability. ZINC05626394 may have potential applications in anti-cancer suppression, especially in combination with antibody drug conjugates (ADCs) and immune checkpoint inhibitors. The efficacy of ZINC05626394 may be limited by different mechanisms, including antigen-related resistance and failure of endocytosis. | ||||||||||||||||||||
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